Efficacy of drug Ondansetron for prevention of low blood pressure (hypotension)

Comparison of Efficacy and Safety Profile of PreEmptive Ondansetron and Ephedrine for prevention of hypotension under Spinal Anaesthesia: A Prospective Double blinded Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/066242

Enrollment

144

Registered

2024-04-24

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I952- Hypotension due to drugs

Interventions

Intervention1: Group O Ondansetron 8mg with normal saline: Patient will receive Ondansetron 8mg diluted to normal saline to make it 5ml total volume given Intravenously as bolus ten minutes before giv

Eligibility

Inclusion criteria

Inclusion criteria: ASA Class I

Exclusion criteria

Exclusion criteria: Patient’s refusal Infection at the site Coagulation abnormality Allergy to study drugs Patient receiving Ondansetron Repeat or failed spinal

Design outcomes

Secondary

Measure	Time frame
To compare hemodynamic changes in both the study groups To compare side effects and complications if anyTimepoint: Intraoperative	—

Primary

Measure	Time frame
To compare the efficacy of the two study drugs for prevention of Incidence of HypotensionTimepoint: Intraoperative	—

Countries

India

Contacts

Public ContactDr Ashutosh kumar

All India institute of medical sciences Gorakhpur

vikram15vardhan@gmail.com9323267123

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026