Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Group A IV MAGNESIUM SULPHATE: The patient will receive Magnesium Sulphate IV (60mg/kg) diluted in 100ml Normal Saline over 10 minutes, 15 minutes before giving IV rocuronium (0.6mg/kg)
Sponsors
NIL
Eligibility
Inclusion criteria
Inclusion criteria: 1. American Society Of Anaesthesiologist (ASA) grading 1-2 2. BMI 18.5-29.9 3. All GA Surgeries lasting for more than 2 hrs
Exclusion criteria
Exclusion criteria: 1.Refused To Participate In The Study 2.Cardiac Conduction Abnormalities 3.Patients Having Neuromuscular Disease 4.known hepatic and renal dysfunction 5.Allergies to study drugs 6.Patients having electrolyte abnormalities 7.Patients on medications known to alter neuromuscular function 8.Patients having expected difficult mask ventilation or difficult laryngoscopy and intubation 9.Pregnant women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ONSET OF NEUROMUSCULAR BLOCKADE OF ROCURONIUMTimepoint: From the time of giving rocurnium to the time of achieving T1(first twitch) less than or equal to 5% | — |
Secondary
| Measure | Time frame |
|---|---|
| HEMODYNAMIC RESPONSE TO LARYNGOSCOPYTimepoint: Just before intubation, during laryngoscopy, just after intubation, 5 mins after intubation;time of first top-up dose of rocuroniumTimepoint: TOF Count 2-3;Time of neuromuscular recoveryTimepoint: TOF ratio more than or equal to 0.9;Total cumulative dose of RocuroniumTimepoint: At the end of last top-up dose | — |
Countries
India
Contacts
Public ContactDr Priyanka Gupta
All India Institute Of Medical Sciences, Rishikesh
Outcome results
None listed