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To assess the efficacy of Metronidazole+Amoxicillin VS Doxycycline VS Azithromycin VS Amoxicillin as an adjunct to Scaling and Root planing (SRP) in the treatment of chronic periodontitis.

EFFECTIVENESS OF SYSTEMIC ADMINISTRATION OF 4 diffrent antibiotics IN CHRONIC PERIODONTITIS - A RANDOMISED CONTROLLED CLINICAL TRIAL - nil

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/04/066213
Enrollment
55
Registered
2024-04-24
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: amoxicillin and metronidazole vs Doxycycline vs Azithromycin vs Amoxicillin as adjunct to scaling and root planing: Amoxicillin and Metronidazole 500 mg and 400 mg once daily respective

Sponsors

saveetha dental college and hospital
Lead Sponsor
vazeeha afrin syed
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Adults aged from 18 years to 50 years. - Stage | and Stage ? periodontitis based on criteria established by the American Academy of Periodontology. - Presence of at least 6 teeth with probing depth = [4 mm] and clinical attachment loss = [2 mm].

Exclusion criteria

Exclusion criteria: History of systemic antibiotic use within the past [3 months]. - Pregnant or lactating individuals. - Known allergies to the study antibiotics. - Severe systemic diseases affecting periodontal health.

Design outcomes

Primary

MeasureTime frame
bleeding on probing pocket depth clinical attachment levelsTimepoint: baseline, 2 weeks and 1 month

Secondary

MeasureTime frame
plaque index gingival indexTimepoint: baseline 2 weeks 1 month

Countries

India

Contacts

Public Contactvazeeha afrin syed

saveetha dental college and hospital,SIMATS UNIVERSITY

152205001.sdc@saveetha.com09618696972

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026