Health Condition 1: R652- Severe sepsis
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: On mechanical ventilation for a minimum period of 24 hours with readiness of weaning as assessed by: 1)recovery from the cause of respiratory failure 2)stable hemodynamic status with no requirement for vasopressors 3)fully conscious with GCS more than or equal to 14 4)Fraction of inspired oxygen(FiO2)less then 0.5,Positive end expiratory pressure(PEEP)less than or equal to 5cm H20,Respiratory rate less than 30,Partial pressure of oxygen(Pao2)/Fraction of inspired oxygen(FiO2) more than 200
Exclusion criteria
Exclusion criteria: 1.Pneumothorax, pleural effusion, collapse, fibrosis 2.Rib fracture, thoracic surgery, thoracotomy 3.History of neuromuscular disease, diaphragmatic palsy, mechanical factor or surgical dressing over the chest. 4.Tracheostomy tube in situ 5.Pregnancy, ascites, morbid obesity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the sensitivity and specificity of ultrasonographic guided parasternal intercostal muscle thickness fraction (PICTF%) for predicting weaning outcome in patients on mechanical ventilation in the intensive care unit. Timepoint: After 10 mins of Starting Spontaneous breathing trail (SBT)for weaning the patient from mechanical ventilation | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the predictive values of diaphragmatic thickness fraction (DTF) and parasternal intercostal muscle thickness fraction (PICTF) on ultrasonography for predicting weaning outcome in patients on mechanical ventilation in the intensive care unit.Timepoint: After 10 mins of Starting Spontaneous breathing trail (SBT)for weaning the patient from mechanical ventilation | — |
Countries
India
Contacts
Vardhman Mahavir Medical College and Safdarjung Hospital