Comparing morphine and dexamethasone as additive to epidural bupivacaine to estimate post operative pain free period.

Comparison of Effectiveness of Morphine versus Dexamethasone as Adjuvant to Epidural Bupivacaine on the Duration of Post Operative Analgesia in Lower Limb Orthopaedic Surgeries - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/066174

Enrollment

Registered

2024-04-23

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexamethasone: Patient will be given epidural top up with 8 ml of 0.1% bupivacaine and 8mg dexamethasone. Control Intervention1: Morphine: Patient will be given epidural top up with 8 m

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiologist grade I and II Patients willing to give informed Consent

Exclusion criteria

Exclusion criteria: Patients with history of long term use of corticosteroids or any analgesics Pregnant women Patients with history of allergy to the study drugs

Design outcomes

Primary

Measure	Time frame
to compare the duration of post operative analgesia between morphine and dexamethasone as adjuvant to bupivacaineTimepoint: 24 hours	—

Secondary

Measure	Time frame
To compare adverse effects and hemodynamic changes between the groupsTimepoint: 24 hours	—

Countries

India

Contacts

Public ContactDr Santhosh M C B

Mandya Institute of Medical Sciences

mcbsanthu@gmail.com9886811263

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026