This study is being conducted to compare two doses of intravenous dexamethasone for prolongation of analgesia in axillary block in patient undergoing mid arm surgeries

A Placebo Controlled study to compare two doses of intra-venous dexamethasone for Prolongation of analgesia in axillary Brachial plexus block . - Nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/066163

Enrollment

Registered

2024-04-23

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: O- Medical and Surgical Health Condition 3: S529- Unspecified fracture of forearm

Interventions

Intervention1: Ultrasound guided axillary brachial plexus block is given in all patients undergoing below mid arm surgeries: All block will be performed with sono site Edge 2 ultrasound machine using

Eligibility

Inclusion criteria

Inclusion criteria: ASA I-III patients undergoing elective below mid arm surgeries under axillary Brachial plexus block and duration of surgery should be less than 3 hours

Exclusion criteria

Exclusion criteria: 1)local infection at injection site or sepsis 2)allergy to any local anaesthetic 3)pt.with known coagulopathy or an anticoagulant therapy 4)pt with GERD,cataract ,glaucoma 5)steroid use within 2 weeks of study period 6)systemic fungal infection ,viral infection 7)patient with nerve entrapment or neuropathy after trauma or diabetic neuropathy and uncontrolled diabetes. 8)patient who refuse to give consent 5)

Design outcomes

Primary

Measure	Time frame
Duration of analgesia is compared between 3 groups of axillary brachial plexus block. 1)d0-i/v NS given 2)d1-i/v 4mg dexamethasone given 3)d2-i/v 8mg dexamethasone givenTimepoint: We will assess efficacy of block at 30min after block . We will assess VAS score at 1)Baseline(preblock) 2) every 1 hourly till 4 hours 3) every 30min till 6 hours 4) 24 hour	—

Secondary

Measure	Time frame
1)Block characteristics (onset and duration ) 2)no.of attempt taken for block 3)duration of sensory block 4)duration of motor block 5)VAS 6)Any complicationsTimepoint: 1)sensory block duration is time in minutes from end of local anaesthesia injection till return of hand and finger sensation (ts) 2)motor block duration is time in minutes from end of local anaesthesia injection till return of hand and finger movement(TM) 3)VAs ( 0-100) acess at before block ,30min after block ,every 1hourly till 4 hour ,then every 30 min interval till next 2 hour .	—

Measure

Time frame

1)Block characteristics (onset and duration ) 2)no.of attempt taken for block 3)duration of sensory block 4)duration of motor block 5)VAS 6)Any complicationsTimepoint: 1)sensory block duration is time in minutes from end of local anaesthesia injection till return of hand and finger sensation (ts) 2)motor block duration is time in minutes from end of local anaesthesia injection till return of hand and finger movement(TM) 3)VAs ( 0-100) acess at before block ,30min after block ,every 1hourly till 4 hour ,then every 30 min interval till next 2 hour .

—

Countries

India

Contacts

Public ContactDr Mangal Ahlawat

PGIMS Rohtak

drmangalahlawat@gmail.com9812989930

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026