To compare the efficacy of carbetocin versus oxytocin in preventing postpartum hemorrhage in women undergoing vaginal delivery- A randomised controlled trial

A randomised controlled trial to compare the efficacy of carbetocin vs oxytocin in preventing postpartum hemorrhage in women undergoing vaginal delivery - Nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/066132

Enrollment

194

Registered

2024-04-23

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O720- Third-stage hemorrhage

Interventions

Intervention1: carbetocin: Carbetocin 100mcg IM Single dose is given immediately after vaginal delivery of the baby for preventing post partum hemorrhage. Control Intervention1: oxytocin: Oxytocin 10I

Eligibility

Inclusion criteria

Inclusion criteria: Singleton pregnancies Parity =3 Undergoing vaginal delivery

Exclusion criteria

Exclusion criteria: Patients with one or more of following were excluded: underlying medical disease, including severe pre-eclampsia, eclampsia,bleeding disorders, thrombocytopenia, cardiovascular diseases, liver and renal diseases. (2) history of oxytocin or carbetocin allergy (3) obstetric complications, such as placental abruption and abnormal placentation.

Design outcomes

Primary

Measure	Time frame
To compare the post-partum blood loss in both the groupsTimepoint: 48 hours	—

Secondary

Measure	Time frame
To compare the pre-partum and post-partum drop in haemoglobin in both the groups To compare the hemodynamic effects of both drugsTimepoint: 4hours	—

Countries

India

Contacts

Public ContactEsther Issac

SRM Institute of Science and Technology

hod.obg.ktr@srmist.edu.in9042038136

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026