Health Condition 1: 3- Administration
Conditions
Interventions
Intervention1: Oral submucous fibrosis: 30 oral submucous fibrosis patients meeting the inclusion and exclusion criteria will be given Oral pentoxifylline 400mg T.D.S for 3months.
Control Interventio
Sponsors
Government College of Dentistry
Eligibility
Inclusion criteria
Inclusion criteria: 1)All new clinically diagnosed cases of OSMF between age group 18-55 years. 2)Patients who were willing to quit gutkha, areca nut and/or with tobacco chewing habit. 3)Patients who were ready to give their consent for the treatment.
Exclusion criteria
Exclusion criteria: 1)Patients who have disclosed medical history for major diseases. 2)Patients with coexisting disease or disorder of the orofacial region other than OSMF which may interfere with the study protocol. 3)Patients with or having a history of oral cancer. 4)Patients with the inadequate reference point (i.e. incisal edges of the central incisors) for measuring interincisal distance. 5)Patients with limited mouth opening reasons other than OSMF.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To eliminate the signs & symptoms, halt disease progression & reduce the predisposition for malignant transformation. Timepoint: baseline 1month 2month 3month 6months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) To assess improvement in mouth opening. 2) To assess relief from intolerance to spicy food. 3) To evaluate difference in pain on opening mouth wide in control & study group. 4) To evaluate difference in cheek flexibility, tongue protrusion, blanching & depapillation of tongue and the extent of fibrous bands. Timepoint: baseline 1month 2month 3month 6months | — |
Countries
India
Contacts
Public ContactDr. Yashika Kewalramani
Government College of Dentistry Indore
Outcome results
None listed