Effect of airway nebulization with local anaesthetics in vital parameters during general anaesthesia

Effect of airway nebulization with lignocaine 2% versus ropivacaine 0.5% on intubation and extubation response in patients undergoing surgery under general anaesthesia - a randomized controlled trial - Nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/066115

Enrollment

Registered

2024-04-23

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: 5 ml of o.5% ropivacaine: 5ml of 0.5 percent ropivacaine solution will be given as nebulization.Nebulization will be done with a 200cm tubing connected from the oxygen port with 100 per

Eligibility

Inclusion criteria

Inclusion criteria: Patients of American Society of Anaesthesiologists physical grade I or II

Exclusion criteria

Exclusion criteria: 1. Patients undergoing head and neck surgeries where cough reflex has to be assessed during extubation 2. Patients with history of recent respiratory infection 3. Patients with history of chronic obstructive pulmonary disease, asthma 4. Anticipated difficult intubation 5. Emergency surgery

Design outcomes

Primary

Measure	Time frame
Hemodynamic stress response during intubation and extubationTimepoint: Outcome will be assessed during intubation and extubation. Data will be then assessed at the end of one year.	—

Secondary

Measure	Time frame
Cough reflexTimepoint: Outcome will be assessed during extubation.Data will be then assessed at the end of one year.	—

Countries

India

Contacts

Public ContactDr Rupendra Singh Thokchom

Regional Institute of Medical Sciences Imphal

penbeeru63@gmail.com9774247043

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026