Comparison of centchroman (a contraceptive)and mefenamic acid (a pain killer) in premenstrual symptoms

Effectiveness between centchroman vs mefenamic acid in premenstrual symptoms - A Randomised Controlled Trial

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/066106

Enrollment

126

Registered

2024-04-23

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N943- Premenstrual tension syndrome

Interventions

Intervention1: Centchroman: 60mg twice a week for 1 month followed by 60mg once a week for 1 month Control Intervention1: Mefenamic acid: 250 mg thrice daily give 5 days before menstruation till the r

Eligibility

Inclusion criteria

Inclusion criteria: Regular menses

Exclusion criteria

Exclusion criteria: Women with medical disorders, patients with breast lump , mammary ductal disease , fibrocystic disease

Design outcomes

Primary

Measure	Time frame
To compare the effectiveness of centchroman and mefenamic acid in premenstrual symptoms (affective symptoms, mastalgia, premenstrual pain)Timepoint: 3 months	—

Secondary

Measure	Time frame
To know the improvement in quality of lifeTimepoint: 3 months	—

Countries

India

Contacts

Public ContactDr A Bupathy

Sri manakula vinayagar medical College and hospital

arunabup@yahoo.co.in8098250579

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026