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Evaluation of additive efficacy of filler material hyaluronic acid combined with melatonin to close black triangle formed in between the teeth after gum surgery.

Evaluation of Additive Efficacy of Hyaluronic acid with Melatonin gel in papilla reconstruction post flap surgery. - Nil

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/04/066082
Enrollment
40
Registered
2024-04-22
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K055- Other periodontal diseases

Interventions

Intervention1: Hyaluronic acid+ melatonin: Hyaluronic acid (0.8% Gengigel) used with 3mg of melatonin powder to be measured using a laboratory weight measuring instrument mixed and introduced into th

Sponsors

Saveetha Dental College and Hospital SIMATS university
Lead Sponsor
Dr Nivedha N
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1 Patients among 18 â?? 45 years of age who has undergone flap surgery within 3 months of interval. 2 Patients with esthetic concern; 3 Having adequate width of attached gingiva 4 The sites with a distance 7 mm from the interdental contact point to the interproximal bone crest and a probing depth of 4 mm at the defective papillary sites were considered for inclusion. 5 Food lodgment in the anterior embrasure; with Class I and Class II papillary loss (Nordland & Tarnow classification, 1982)

Exclusion criteria

Exclusion criteria: 1 Patient who received radiotherapy, chemotherapy, immunosuppressive treatments, systemic corticosteroids and/or anticoagulants the 30 days prior to intervention. 2 Patients with known history of allergy having known history of allergy, systemic or blood borne diseases undergoing orthodontic treatment. 3 prolonged treatment with non-steroidal anti-inflammatory drugs (NSAIDs) or similar medications. 4 smokers; lactating or pregnant females. 5 presence of any restoration in maxillary or mandibular anterior region

Design outcomes

Primary

MeasureTime frame
Papillary Width Papillary Deficient Height Width of keratinized gingiva Deficient AreaTimepoint: Baseline 3months 6months

Secondary

MeasureTime frame
Probing depth Clinical attachment levels Plaque index Papilla presence indexTimepoint: Baseline 3months 6months

Countries

India

Contacts

Public ContactDr Sankari Malaiappan

Saveetha dental college and hospital, SIMATS University

sankari@saveetha.com9840285905

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026