Health Condition 1: I671- Cerebral aneurysm, nonruptured Health Condition 2: I679- Cerebrovascular disease, unspecified Health Condition 3: I619- Nontraumatic intracerebral hemorrhage, unspecified Health Condition 4: I607- Nontraumatic subarachnoid hemorrhage from unspecified intracranial artery Health Condition 5: I699- Sequelae of unspecified cerebrovascular diseases
Conditions
Interventions
Intervention1: Nitroglycerine plus verapamil: Nitroglycerine 200 µg plus verapamil 2.5 mg to be given as a single bolus dose while doing transradial diagnostic cerebral angiography immediate after rad
Sponsors
Post Graduate Institute of Medical Education and Research Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: Age more than 18 years Indications for diagnostic cerebral angiography
Exclusion criteria
Exclusion criteria: 1. Age less than 18 years 2. Radial artery diameter less than 1.8 mm 3. Hypotension(Systolic Blood Pressure below 90 mm hg) 4. Severe left ventricular dysfunction(left ventricular ejection fraction less than 35%) 5. Significant Bradycardia (heart rate below 50 betas per minute) 6. History of Raynauds phenomenon in the upper limb 7. Vasculitis 8. Severe atherosclerotic segmental stenotic disease in the upper limb arteries 9. Only functional limb/injured limb 10. Contraindications of diagnostic DSA-deranged RFTs, Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the incidence and severity of radial artery spasm in both groups of patients undergoing transradial diagnostic cerebral angiographyTimepoint: At baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| Influence of the baseline characteristics of patients in each group on the occurrence of radial artery spasmTimepoint: At baseline;Occurrence of radial artery occlusionTimepoint: 24 hours post procedure & 4 weeks post procedure;Outcome of hemodynamic events in each group (includes decrease in the systolic blood pressure, decrease in the heart rate, fluid support requirement , need of any additional drug, etc).Timepoint: At baseline | — |
Countries
India
Contacts
Public ContactDr Tiwari Vivek Premshankar
Post Graduate Institute of Medical Education and Research, Chandigarh
Outcome results
None listed