FindTrial
Sign In

IMPACT OF INTERVENTION WITH FRUSEMIDE(LASIX)/DIALYSIS COMPARED WITH STANDARD INTERVENTION IN CRITICALLY ILL/ICU PATIENTS ON DEATH IN A TERTIARY CARE HOSPITAL

IMPACT OF PROTOCOLIZED DE-RESUSCITATION WITH FRUSEMIDE/RENAL REPLACEMENT THERAPY COMPARED WITH STANDARD INTERVENTION IN CRITICALLY ILL PATIENTS ON MORTALITY IN A TERTIARY CARE HOSPITAL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/04/066053
Enrollment
198
Registered
2024-04-22
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R098- Other specified symptoms and signsinvolving the circulatory and respiratory systems

Interventions

Intervention1: FRUSEMIDE/RENAL REPLACEMENT THERAPY STANDARD THERAPY: Frusemide (Injection Lasix 20 mg) 0.5 mg/kg bolus f/b infusion 2.5 mg/hour ? titrated to achieve negative balance 1L /day after D3

Sponsors

AMRITA SHAH
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: At least 2 days of ICU admission Older than 18 years

Exclusion criteria

Exclusion criteria: 1. Patient’s refusal. 2. Patient younger than 18 years. 3. Length of ICU stay 4. Lactates >4 5. Norepinephrine/epinephrine > 0.2 mcg/kg/min/ >1 vasopressor in use 6. Patients with subarachnoid haemorrhage

Design outcomes

Primary

MeasureTime frame
Mortality at 28 daysTimepoint: 28 DAYS—

Secondary

MeasureTime frame
Hospital and ICU mortality Mechanical ventilator free days ICU length of stay (ICU-LOS) New adverse effects – hypernatremia, metabolic alkalosis, new AKI Change in SOFA Score Timepoint: 28 DAY—

Countries

India

Contacts

Public ContactAMRITA SHAH

Manipal hospitals yeshwanthpur

prangap939@gmail.com9864872622

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026