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Prediction of hypertensive disorder of pregnancy in first trimester using blood pressure,ultrasonography and pregnancy associated blood marker.

Prospective observational study for prediction of pre-eclampsia at 11 to 14 weeks of gestation using mean arterial pressure, uterine artery doppler and pregnancy-associated plasma protien-A. - NIL

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/04/066044
Enrollment
96
Registered
2024-04-22
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z00-Z99- Factors influencing health status and contact with health services

Interventions

Intervention1: nil: nil Control Intervention1: nil: nil

Sponsors

Bhaktivedanta Hospital and Research Institute
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Pregnant females of age 18 to 45 years who are registered and planning to deliver at bhakti Vedanta hospital and willing for regular antenatal visits. 2. Willing to participate in study.

Exclusion criteria

Exclusion criteria: Patients with fetal chromosomal abnormality. Patients diagnosed with multifetal pregnancy. Patients having chronic hypertension or diagnosed with pre-eclampsia in previous pregnancy. Patients having renal disease obesity (BMI more than 40) Autoimmune disorder like SLE Not willing to participate in study

Design outcomes

Primary

MeasureTime frame
Increased chances of development of pre-eclampsia are seen with PAPP-A values less than 0.5 MOM at 11 to 14 weeks,High mean arterial pressure increases the risk of pre-eclampsia, Abnormal uterine artery pulsatility index values have higher risk for development of pre-eclampsia. Timepoint: at 11 to 14 weeks, at 20 to 34 weeks, at the time of delivery

Secondary

MeasureTime frame
Assessment of severity of pre-eclampsia using PAPP-A, mean arterial pressure and uterine artery pulsatility index values,Association of the time of development of pre-eclampsia i.e., early or late onset with PAPP-A values, mean arterial pressure and uterine artery pulsatility index,Correlation of fetal growth restriction with low PAPP-A values and high uterine artery pulsatility index,Evaluation of neonatal complications such as apgar score, birth weight and requirement of nicu admission in patients of pre-eclampsia Timepoint: at 11 to 14 weeks, at 20 to 34 weeks, at the time of delivery

Countries

India

Contacts

Public ContactDr Gargee Sharma

BhaktiVedanta Hospital and Research Institute

drkamalapriyat@gmail.com8879614447

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026