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Effect of intraoperative administration of three types of intravenous fluids on postoperative serum sodium levels in patients undergoing lower limb orthopedic surgeries

Effect of intraoperative use of Isotonic Saline, Ringer’s Lactate and a combination of both on postoperative serum sodium levels in lower limb orthopedic surgeries- A double blind randomized controlled trial - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/04/065984
Enrollment
90
Registered
2024-04-19
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Group IS +RL: Group IS +RL: Patients will be administered alternatively with intravenous Isotonic saline and Ringer’s lactate intraoperatively and postoperatively from the time pati

Sponsors

SDM College of Medical Sciences and Hospital, Dharwad
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients scheduled for lower limb orthopedic surgeries ASA physical status 1 and 2

Exclusion criteria

Exclusion criteria: Patients with abnormal serum sodium levels on the day of surgery Patients with Acute kidney injury head injury congestive cardiac failure liver cirrhosis hyperglycemia Pregnant women Patients on medications such as thiazide diuretics and warfarin Any contraindication to subarachnoid block

Design outcomes

Primary

MeasureTime frame
Change in serum sodium levels from preoperative to postoperative periodTimepoint: time point A :preoperative value on the morning of surgery time point B: 6h after surgery time point C: 24h after time point B—

Secondary

MeasureTime frame
) Incidence of post operative nausea and vomiting in the first 24 hours after surgeryTimepoint: time point C: 24 h after time point B (6 h after surgery);incidence of hyponatremiaTimepoint: time point B: 6h after surgery time point C: 24h after time point B;Incidence of post operative confusion/ delirium in the first 24 hours after surgeryTimepoint: time point A :preoperative value on the morning of surgery time point B: 6h after surgery time point C: 24h after time point B;length of hospital stayTimepoint: at the time of discharge—

Countries

India

Contacts

Public ContactArchana A Bharadwaj

SDM College of Medical Sciences and Hospital, Dharwad

archana.a.b16@gmail.com8437373388

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026