To provide post operative pain relief in patients undergoing lumbar vertebral laminectomies by using erector spinae block with levobupivacaine and bupivacaine along with dexmedetomidine and there comparison between two groups under ultrasound guidance

Comparison of levobupivacaine with dexmedetomidine Vs bupivacaine with dexmedetomidine in ultrasound guided erector spinae block for post operative analgesia in patients undergoing lumbar vertebral laminectomy – A randomized double blinded prospective study. - A randomized prospective study

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/065972

Enrollment

Registered

2024-04-19

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Leobupivacaine in erector spinae block for patients undergoing lumbar laminectomies.: Erector spinae block with 15 ml of 0.25% levobupivacaine with 0.5 mcg dexmetomidine for 5 to 10 mi

Eligibility

Inclusion criteria

Inclusion criteria: 1) ASA grade I – II patients 2) Aged 18 – 65 years 3) Patients willing to participate 4) Patients undergoing lumbar laminectomies and discectomies.

Exclusion criteria

Exclusion criteria: 1) Patient who refused to participate 2) Morbidly obese patients 3) Pregnancy 4) Severe hepatic insufficiency 5) Severe renal insufficiency 6) Spinal deformities 7) Drug allergies used in the study 8) Cardiac or respiratory compromise 9) Coagulation profile abnormalities 10) Patients on beta blockers 11) Patients with neurological deficit

Design outcomes

Primary

Measure	Time frame
1) Duration of analgesia ( after giving block)initial use of rescue analgesia for surgical site painTimepoint: 1) Duration of analgesia 6hr to 8hr ,12hrs,16hrs till 48hrs after giving block)initial use of rescue analgesia for surgical site pain( if patient complains of pain inj .ketrolac should be given)pain initial use of rescue analgesia for surgical site pain	—

Secondary

Measure	Time frame
1) To evaluate the efficacy of levobupivacaine with dexmedetomidine and bupivacaine with dexmedetomidine in terms of maximum visual analogue scale (VAS) pain score and consumption of rescue analgesia. 2) To assess time for mobilization for the patients undergoing lumbar laminectomies. 3) Comparison of intraoperative hemodynamics between two groups. 4) Comparison of readiness for discharge in the two groups.Timepoint: VISUAL ANALOGUE SCALE	—

Measure

Time frame

1) To evaluate the efficacy of levobupivacaine with dexmedetomidine and bupivacaine with dexmedetomidine in terms of maximum visual analogue scale (VAS) pain score and consumption of rescue analgesia. 2) To assess time for mobilization for the patients undergoing lumbar laminectomies. 3) Comparison of intraoperative hemodynamics between two groups. 4) Comparison of readiness for discharge in the two groups.Timepoint: VISUAL ANALOGUE SCALE

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Countries

India

Contacts

Public ContactDr erana rebecca

nizams institute of medical sciences,panjagutta hyderabad

abinash.patro@gmail.com9204785946

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026