Comparision of USG guided Transversus Abdominis Plane Block for analgesia during first 24 hours after unilateral hernia surgery

A randomized double blinded comparative interventional study to assess the post operative analgesic effect of Magnesium sulphate versus Dexamethasone as adjuvants to Bupivacaine in ultrasound guided Transversus Abdominis Plane Block in open unilateral hernia surgeries - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/065963

Enrollment

105

Registered

2024-04-19

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K409- Unilateral inguinal hernia, without obstruction or gangrene

Interventions

Intervention1: Transversus Abdominis Plane TAP block using 20 ml of 0.25% Bupivacaine+ 250 mg of MgSO4 in 35 patients: USG guided TAP block using 20 ml of 0.25% Bupivacaine +250 mg MgSO4 in patients u

Eligibility

Inclusion criteria

Inclusion criteria: Patients consenting to participate between age 18-60 years undergoing elective open unilateral hernia surgeries under spinal anaesthesia. Patients belonging to ASA grade I and II. Weight between 40-80 kgs.

Exclusion criteria

Exclusion criteria: Patients not consenting to participate Patients having history of chronic use of analgesia for pain Patients allergic to drugs used in the study Patients with psychosis or gross neurological disorders Patients with body mass index more than 35

Design outcomes

Primary

Measure	Time frame
1 To assess and compare the mean dose of rescue analgesic requirement in first 24 hours conferred by bupivacaine with magnesium sulphate versus bupivacaine with dexamethasone in USG guided TAP block in open unilateral hernia surgeries 2 To compare and assess NRS scores between two groups 3 To assess and compare the level of patient satisfaction betweeen two groups using patient satisfaction indexTimepoint: 1 To assess and compare the mean dose of rescue analgesic requirement in first 24 hours conferred by bupivacaine with magnesium sulphate versus bupivacaine with dexamethasone in USG guided TAP block in open unilateral hernia surgeries 2 To assess and compare NRS scores between two groups 3 To assess and compare the level of patient satisfaction betweeen two groups using patient satisfaction index	—

Measure

Time frame

1 To assess and compare the mean dose of rescue analgesic requirement in first 24 hours conferred by bupivacaine with magnesium sulphate versus bupivacaine with dexamethasone in USG guided TAP block in open unilateral hernia surgeries 2 To compare and assess NRS scores between two groups 3 To assess and compare the level of patient satisfaction betweeen two groups using patient satisfaction indexTimepoint: 1 To assess and compare the mean dose of rescue analgesic requirement in first 24 hours conferred by bupivacaine with magnesium sulphate versus bupivacaine with dexamethasone in USG guided TAP block in open unilateral hernia surgeries 2 To assess and compare NRS scores between two groups 3 To assess and compare the level of patient satisfaction betweeen two groups using patient satisfaction index

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Secondary

Measure	Time frame
1.To determine and compare the difference in hemodynamic ( heart rate, systolic blood pressure, diastolic blood pressure, mean arterial blood pressure, spo2) differences in both groups. 2.To observe the incidence of side effects and complications if any.Timepoint: 1. To determine the change in the hemodynamic parameters (HR, SBP,DBP,MAP,Spo2) in groups 24 hours post operatively. 2. To observe side effect or comlipcations,if any	—

Measure

Time frame

1.To determine and compare the difference in hemodynamic ( heart rate, systolic blood pressure, diastolic blood pressure, mean arterial blood pressure, spo2) differences in both groups. 2.To observe the incidence of side effects and complications if any.Timepoint: 1. To determine the change in the hemodynamic parameters (HR, SBP,DBP,MAP,Spo2) in groups 24 hours post operatively. 2. To observe side effect or comlipcations,if any

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Countries

India

Contacts

Public ContactDr Kartika Phulwaria

SMS Medical College

kartikaphulwaria01@gmail.com7597535191

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026