Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx
Conditions
Interventions
Intervention1: ASSESSING TOPICAL METHYLENE BLUE EFFICACY FOR RADIATION-INDUCED ORAL MUCOSITIS PAIN: A SINGLE ARM PHASE II CLINICAL TRIAL: In instances where patients report a pain score greater than 4
Sponsors
Navas Bright
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age more than 18 years 2. Oral cavity and oropharynx cancer patients receiving radiation or chemoradiation 3. Oral cavity pain with NRS =4 and not on analgesic for oral pain. 4. Pain score more =7, with or without analgesia for oral pain 5. Any grade of oral mucositis 6. All stages of cancer with cancer-related pain adequately controlled before radiation 7. Voluntary written consent.
Exclusion criteria
Exclusion criteria: 1.Oro-cutaneous fistula 2.Inability to rinse/gargle/no mouth opening 3Known allergy to methylene blue 4.Cognitive impairment and inability to consent 5.Confused/ agitated patient 6.Patient with cognitive impairment 7.Patients undergoing re-radiation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluate pain relief with topical methylene blue 0.025% in patients with radiation-induced oral mucositis.Timepoint: baseline, 1st hour, every day once for 2 weeks,then alternate day for 2 weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Oral functioning of the patient with radiation induced OM on methylene blue rinse. 2.Dose of systemic analgesics and adjuvants in patients receiving methylene blue. 3. Side effects of methylene blue on topical use for oral mucositis. Timepoint: Four weeks of starting intervention. | — |
Countries
India
Contacts
Public ContactNavas Bright
Cancer Institute (WIA)
Outcome results
None listed