Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Administration of Indo cyanine green dye intraoperatively for safe laparoscopic cholecystectomy: 10 ml of 0.025mg/ml of ICG bile solution is injected into fundus of gall bladder intraop
Sponsors
Department of Surgical Gastroenterology and GI oncology
Eligibility
Inclusion criteria
Inclusion criteria: elective and quasi emergency indication for laparoscopic cholecystectomy
Exclusion criteria
Exclusion criteria: 1) Pregnancy or lactation. 2) Previous adverse reactions to ICG. 3) Emergency gallbladder surgery. 4) Previous suspicion of gallbladder cancer. 5) Inability to understand the information about the study. • Refusal to participate in the study. • Perforated GB with peritonitis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the quality of visualisation of biliary structures and to measure the fluorescence intensity in the cystic duct and common bile duct junction after ICG injection during laparoscopic cholecystectomyTimepoint: Outcome is assessed after the surgery on the same day of surgery (one time measurement) | — |
Secondary
| Measure | Time frame |
|---|---|
| • To analyse the influence of various factors on the results of NIRF-LC • Body mass index (BMI) • Liver disease (fatty liver, hepatitis & cirrhosis) • Underlying biliary disease (biliary colic, choledocholithiasis, cholecystitis & pancreatitis) • ERCP interventions • Intraoperative (Rate of conversion to open, Inadvertent CBD injury & postoperative complications in NIRFC-LC • Duration of surgery • To assess the extent to which liver fluorescence background (liver to-ducts contrast) was perceived as a disturbance. Timepoint: Outcome is assessed after the surgery on the same day of surgery.(one time measurement) | — |
Countries
India
Contacts
Public ContactArun Raja Alagendran
thanjavur medical college hospital
Outcome results
None listed