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Outcomes of sevoflurane and propofol on left ventricular diastolic function in patients undergoing coronary artery bypass graft surgery.

Outcomes of Sevoflurane and Propofol on Left Ventricular Diastolic Function In Patients Undergoing Coronary Artery Bypass Graft using Cardiopulmonary Bypass - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/04/065898
Enrollment
50
Registered
2024-04-18
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I251- Atherosclerotic heart disease of native coronary artery

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

ARMY HOSPITAL REASERCH AND REFERAL NEW DELHI India
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients undergoing elective coronary artery bypass graft surgery using cardiopulmonary bypass

Exclusion criteria

Exclusion criteria: LEFT VENTRICULAR EJECTION FRACTION LESS THAN 30% CARDIOMYOPATHY PRE EXISTING VALVULAR HEART DISEASE GRADE 4 DIASTOLIC DYSFUNCTION ATRIAL FIBRILLATION SIGNIFICANT PULMONARY DISEASES (EG.ILD,PTE..) EMERGENCY PROCEDURE OESOPHAGEAL PATHOLOGY

Design outcomes

Primary

MeasureTime frame
To evaluate left ventricular diastolic function by measuring Peak flow velocity of early diastolic filling E Early diastolic mitral annulus velocity e using Transesophageal echocardiography(TEE) under sevoflurane or propofol based anaesthesia in patients undergoing Coronary artery bypass graft on cardiopulmonary bypass Timepoint: 48hrs—

Secondary

MeasureTime frame
To compare other parameters of diastolic function between sevoflurane and propofol group ; Late diastolic filling(A), Deceleration time (DT) , Peak systolic flow velocity (S), Peak diastolic flow velocity (D), S/D ratio, Peak reversal atrial flow (Ar), Duration of reverse atrial flow (Ar dur), Late diastolic mitral annulus velocity(a’). To determine the Vasoactive inotropic Score (VIS ) between sevoflurane group and propofol group . To assess the duration of Mechanical ventilation & ICU stay between sevoflurane group and propofol group Timepoint: 7 days—

Countries

India

Contacts

Public ContactDR COL BHAVNA HOODA

ARMY HOSPITAL R AND R NEW DELHI

bhavnahooda2007@rediffmail.com9910663810

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026