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Effectiveness of cold therapy on prevention of CIPN among patients receiving chemotherapy.

Effectiveness of cold therapy on prevention of Chemotherapy induced peripheral neuropathy in patients receiving neurotoxic drugs- A randomized controlled trial.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/04/065873
Enrollment
410
Registered
2024-04-16
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Cryotherapy: INTERVENTION ON COLD THEARPY (cold mittens and socks): It involves providing gel ice packs in the form of customized mittens and socks, covering the wrists and ankles of th

Sponsors

Sukhpal Kaur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: i. Patients suffering from cancer undergoing chemotherapy for the first time with neuro-toxic drugs. ii. Patients willing to participate iii. Above 18 years

Exclusion criteria

Exclusion criteria: i. Known case of Peripheral neuropathy(Diabeteic neuropathy, Raynaud’s syndrome, carpal tunnel syndrome) ii. Patients who are unable to report parasthesia and pain iii. Patients undergoing palliative chemotherapy

Design outcomes

Primary

MeasureTime frame
These are the intensity of the symptoms – paraesthesia, burning, and pain that will be assessed using the NCI- CTCAE guidelines and EORTC CIPN-20 questionnaires. Timepoint: Outcome variables of the participants will be assessed at before administrating each chemotherapy cycle, and at after 30 minutes of each chemotherapy cycle.

Secondary

MeasureTime frame
Quality of Life using EORTC-C30 toolTimepoint: At baseline, 3 months & at 6 months

Countries

India

Contacts

Public ContactDr Sukhpal Kaur

National Institute of Nursing Education, PGIMER

sukhpal.trehan@yahoo.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026