Health Condition 1: D499- Neoplasm of unspecified behavior of unspecified site
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Newly diagnosed patients with stages I to III cancers planning to receive a definitive number of platinum-based compounds chemotherapy. 2) Patients who are given Taxanes and Platinum-based compounds – Cisplastin, Carboplatin and Oxaliplatin 3) 3) Patients having Grade I or II cognitive impairment according to National Cancer Institute –common toxicity criteria. 4) Planned to receive a minimum of 4 cycles of chemotherapy treatment with either of the chemotherapy agents (Platinum based compound) 5) Both Male and female aged grouped between 14-70 years. 6) Patients who are given drugs according to approval of national cancer board
Exclusion criteria
Exclusion criteria: 1) Patients having Pre-existing cognitive impairment. 2) Patient having Traumatic Brain Injury. 3) Patients having a previous history of any psychological condition that could impair cognitive function. 4) Patients who did not perceive any chemotherapy cycle after cancer treatment. 5) Patients with a previous history of cancer and chemotherapeutic drugs. 6) Those who were having any neurological disorders in the brain and spinal cord such as Alzheimer’s disease (AD), Lewy body disease, stroke (CVA), Huntington’s disease, MS, ALS, frontotemporal dementia, and vascular dementia; use of medication known to have a negative impact on cognition (benzodiazepines). 7) Use of antipsychotics and cholinesterase inhibitors (CHEIs); current or recent (past 6 months) alcohol or substance use disorder; any behavioural changes like depression, anxiety, stress, other systemic diseases likely to impair cognition, such as hypothyroidism, de ?ciency of folic acid or vitamin B12, or viral infection (syphilis, HIV); vision and speech impairment (aphasia).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Mini Mental State Examination 2.Montreal Cognitive Assessment 3.Functional Assessment of Cancer Therapy CognitiveTimepoint: Baseline data will be collected and data analysis will be done after 4 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 2. Patient Specific Functional ScaleTimepoint: Baseline data will be collected and data analysis will be done after 4 weeks | — |
Countries
India
Contacts
Ravi Nair Physiotherapy College Datta Meghe Institute of Higher Education and Research