A study to show the effect Of Vitamin D Supplementation On Serum Methylglyoxal in Diabetic Retinopathy patients

Effect Of Vitamin D Supplementation On Serum Levels Of Methylglyoxal In Patients Of Diabetic Retinopathy - Nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/065762

Enrollment

120

Registered

2024-04-16

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E103- Type 1 diabetes mellitus with ophthalmic complications Health Condition 2: E113- Type 2 diabetes mellitus with ophthalmic complications

Interventions

Intervention1: Vitamin D3: 60000IU once in a week for 12 weeks Control Intervention1: Placebo: once in a week for 12 weeks

Eligibility

Inclusion criteria

Inclusion criteria: Patients with Non Proliferative and Proliferative Diabetic Retinopathy

Exclusion criteria

Exclusion criteria: i. Patients receiving vitamin D and calcium supplements. ii. Patients taking any other medication that could change vitamin D metabolism, such as Rifampicin or Phenytoin. iii. Patients with very low vitamin D / sufficient vitamin levels.

Design outcomes

Primary

Measure	Time frame
serum levels of methylglyoxal after vitamin D supplementationTimepoint: 12 weeks	—

Secondary

Measure	Time frame
serum methylglyoxal in various grades of diabetic retinopathyTimepoint: 12 weeks	—

Countries

India

Contacts

Public ContactGoli Sri Likhitha

Aligarh Muslim University

s_zrab@yahoo.com7993066959

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026