Health Condition 1: O720- Third-stage hemorrhage
Conditions
Interventions
Intervention1: injection of uterotonic agents: intravenous injection carbetocin 100mcg bolus over 1 minute and oxytocin 20IU in 1000ml Normal saline(0.9%) at 150ml/hr given after delivery of anterior
Sponsors
Tezpur medical college and hospital
Eligibility
Inclusion criteria
Inclusion criteria: Parturients of the ASA grade 1 and 2 with gestation of 37 weeks or more, who had an elective cesarean delivery under spinal anesthesia with risk factors of postpartum haemorrhage such as multiple pregnancy,two or more previous cesarean section,presence of uterine fibroids,previous myomectomy,past history of postpartum haemprrhage,prolonged labor,fetal macrosomia,BMI 35 and more and fetal malformations with polyhydramnios
Exclusion criteria
Exclusion criteria: ASA garde 2, allergy to study drugs,patients contraindicated for spinal anesthesia,Declined to participate,premature rupture of memebrane,pregnancy induced hypertension,antepartum haemorrhage,patients in active labor,inadequate block after apinal anaesthesia,history of epilepsy,diabetes mellitus,ischemic heart disease,cerebrovascular disease,hepatic and renal disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the efficacy of Oxytocin and carbetocin in terms of adequate uterine contractility and prevention of intraoperative blood lossTimepoint: To assess the efficacy of Oxytocin and carbetocin in terms of adequate uterine contractility and prevention of intraoperative blood loss in first 24 hrs of delivery | — |
Secondary
| Measure | Time frame |
|---|---|
| compare the heamodynamic effects of carbetocin and oxytocin(HR,MAP,ECG) to asses the need for additional uterotonics in cesarean section at high risk of PPH adverse effects of Oxytocin and carbetocinTimepoint: heamodynamic stability in each group for 24 hrs | — |
Countries
India
Contacts
Public ContactDilip kumar saloi
Tezpur medical college and hospital
Outcome results
None listed