To compare the effectiveness of Ondansetron and Palonosetron in reducing post-surgery nausea and vomiting for patients undergoing general anesthesia.

Comparative study between Ondansetron and Palonosetron in prevention of Postoperative nausea vomiting under general anaesthesia -Double blinded randomised control study. - Nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/065741

Enrollment

134

Registered

2024-04-16

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Comparative study between Ondansetron and Palonosetron in prevention of PONV under general anaesthesia.: To compare the efficacy of Palonosetron and Ondansetron in preventing PONV in pa

Eligibility

Inclusion criteria

Inclusion criteria: - ASA physical status I, II - Between 18 to 65 yrs. of age. - Both genders

Exclusion criteria

Exclusion criteria: Patient refusal - Allergic to study drugs - Pregnant women - History of motion sickness, acid peptic disease - Patients on any anti emetics 24hrs prior to surgery

Design outcomes

Primary

Measure	Time frame
Complete response assessed by incidence of nausea ,vomiting and use of rescue anti emeticsTimepoint: 1 Year	—

Secondary

Measure	Time frame
1) Patient satisfaction 2) Side effects - headache, dizziness.Timepoint: 1 year	—

Countries

India

Contacts

Public ContactDr Lahari priya

Dr Rangarajan Memorial Hospital

drsasi123@yahoo.co.in9940666716

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026