Health Condition 1: O- Medical and Surgical
Conditions
Sponsors
Lifebox foundation
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients undergoing major elective oncologic surgery (For example, radical gastrectomy, pancreatic resection, hepatectomy, abdominal compartment resection, radical nephrectomy, retroperitoneal lymph node dissection, radical cystectomy, radical prostatectomy, colorectal resection, total abdominal hysterectomy and salpingo-oophorectomy, and cytoreductive surgeries). 2. Patients requiring an arterial line as part of their standard-of-care.
Exclusion criteria
Exclusion criteria: 1. Patients undergoing emergency surgery. 2. Hemodynamically unstable patients requiring inotrope support. Hemodynamically stable patients with elective low-dose intra-operative inotrope support of up to 0.05mcg/kg/min will still be included. 3. Haemoglobin less than or equal to 8g/dL at the time of surgery. 4. On mechanical ventilation prior to surgery. 5. Pre-existing local skin or nail disorders preventing accurate measurement of SpO2 by pulse-oximeter. 6. Patients with intrathoracic surgical procedures; to avoid potential confounding factors related to lung parenchymal resections, single-lung ventilation or mediastinal dissection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of patients with Occult hypoxemiaTimepoint: Pulse oximetry readings will be obtained at the time of intra-operative and immediate post-operative sampling for ABGA | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Bias in measurement of arterial saturation 2. In-hospital mortality defined as death due to any cause from date of inclusion to date of discharge from the hospital. 3. Length of ICU stay to be measured in hours from time of shifting into ICU after surgery to time of transfer to the ward from ICU. 4. Post-operative extubation rate defined as proportion of patients being extubated at the end of surgery, prior to shifting from the operating room. 5. Duration of hospital stay defined as number of days from date of surgery to the date of discharge. 6. Post-operative pulmonary complications will be defined in accordance with the European Peri-operative Clinical Outcome (EPCO) definitions. 7. Serum lactate levels will be measured in the samples collected for arterial blood gas analysis. Mean and standard deviation of all intra-operative serum lactates levels of each patient will be calculated. Timepoint: At the time of intra-operative and immediate post-operative sampling for ABGA | — |
Countries
India
Contacts
Public ContactDr Reshma Ambulkar
Tata Memorial Centre
Outcome results
None listed