Health Condition 1: M059- Rheumatoid arthritis with rheumatoid factor, unspecified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: All adult patients above 18 years with Rheumatoid Arthritis according to the 2010 ACR/EULAR criteria.
Exclusion criteria
Exclusion criteria: 1.Rheumatoid Arthritis patients with manifest CVD such as Angina,Myocardial Infarction,Stroke,Peripheral Vascular Disease,Gangrene,Heart Failure(or those who have undergone Percutameous Transluminal Coronary Angioplasty and/or coronary Artery Bypass Graft) 2.Known case of diabetes mellitus and chronic kidney disease(eGFR 3.Smoking 4.Patient taking statins 5.Overlap with other connective tissue disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.To stratify and identify high cardiovascular risk in Rheumatoid Arthritis using ASCVD score,QRISK-3 Score,FRS-CVD Score and ERS-RA Score. 2.To compare performance of each score with gold standard CIMT and/or Carotid Plaque in identifying high cardiovascular risk among patients of Rheumatoid Arthritis.Timepoint: Baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Whether any combination(s) or EULAR modification of these risk scores can improve the sensitivity and accuracy to detect Rheumatoid Arthritis patients at high risk of Cardiovascular Disease. 2.Whether simple indices each such as Total cholesterol/HDL (Atherogenic ratio) ,hsCRP and ApoB/ApoA1 ratio can detect Rheumatoid Arthritis patients at high risk of cardiovascular disease.Timepoint: Baseline | — |
Countries
India
Contacts
Maulana Azad Medical College