FindTrial
Sign In

Comparison between Lignocaine HCL and Bupivacaine HCL local anesthetics when used as local application for pain control in mandibular third molar surgery

Comparative evaluation of efficacy of Lignocaine HCL and Bupivacaine HCL used as a local drug delivery system for pain control after impacted mandibular third molar surgery: A single blinded randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/04/065631
Enrollment
72
Registered
2024-04-12
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K011- Impacted teeth

Interventions

Intervention1: 3ML OF 0.5 % Bupivacaine HCL soaked in Absorbable gelatin sponge As local drug delivery: Local application of 0.5% Bupivacaine HCL soaked in Absorbable gelatin sponge in third molar soc

Sponsors

Dr Ayushi Srivastava
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patient willing to participate in the study within age group of 18-50 non smokers moderately difficult pederson score 4-6 ASA status I normal bleeding and clotting time

Exclusion criteria

Exclusion criteria: Patients who are not willing to participate in the study. Patients with presence of any systemic disorders. Patients with previous history of radiation therapy. Patients who had undergone organ transplantation. Patients allergic to anaesthetic agent. Pregnant or lactating female subjects.

Design outcomes

Primary

MeasureTime frame
To evaluate and compare the postoperative pain on using Lignocaine HCL and Bupivacaine HCL soaked in Absorbable gelatin sponge when placed in the extraction socket after impacted mandibular third molar surgery. Postoperative pain will be measured using Visual Analogue Scale.Timepoint: Postoperative pain will be checked at following intervals postoperatively: 4 hours 8 hours 12 hours 1 day 2 day 3 day 4 day 5 day 6 day 7 day—

Secondary

MeasureTime frame
1- to evaluate patients satisfaction score done using 5 point scale, 1- dissatisfied 2- rather dissastisfied 3- neither 4- rather satisfied 5- satisfied 2-to evaluate analgesic rescue doses, reported back by the patient. 3- to evaluate adverse effect like edema, trismus.Timepoint: Patient satisfaction towards postoperative pain will be checked at following intervals postoperatively: 4 hours 8 hours 12 hours 1 day 2 day 3 day 4 day 5 day 6 day 7 day adverse effect will be evaluated on post operative day 2 & day 7 resue analgesic dose will be checked on the 7th day postoperatively—

Countries

India

Contacts

Public ContactDr Tejraj P Kale

K.L.E.V.K Institute of Dental Sciences

tejrajkale@yahoo.com9448472891

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026