Comparison of fentanyl and nalbuphine in attenuating blood pressure and heart rate during laryngoscopy in patients undergoing general anaesthesia.

Comparative study of intravenous bolus doses of nalbuphine with fentanyl in attenuating hemodynamic response to laryngoscopy in patients undergoing nasal intubation for oral and maxillofacial surgery (OMFS) under general anesthesia - Nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/065626

Enrollment

200

Registered

2024-04-12

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intravenous bolus premeditation dose of nalbuphine: Administration of intravenous bolus dose of nalbuphine as premedication in patients undergoing maxillofacial surgeries to see their e

Eligibility

Inclusion criteria

Inclusion criteria: Undergoing nasal intubation in oral and maxillofacial surgery. Patient belonging to American society of Anaesthesiologist physical 1 and 2.

Exclusion criteria

Exclusion criteria: Age >60 or Preoperative hypertension, coronary artery disease (CAD), cardiac conduction defects, congenial heart disease, hemodynamic instability and associated comorbidity. Obesity ( body mass index >30 kg per square meter). Mouth opening less than or equal to 2.5 fingers or inability to do laryngoscopy. MPG grade 4. Patients with nasal fracture.

Design outcomes

Primary

Measure	Time frame
Compare the efficacy between nalbuphine and fentanyl in attenuating hemodynamic response to laryngoscopy and nasal intubation.Timepoint: Intraoperatively	—

Secondary

Measure	Time frame
Compare Post operative sedation Compare post operative pain.Timepoint: Post operatively	—

Countries

India

Contacts

Public ContactAtul Kumar Singh

Institute of Medical Sciences, BHU

atulksingh84@gmail.com8317010317

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026