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Effect of probiotics in babies with jaundice

To study the efficacy of Probiotics along with Phototherapy and phototherapy alone in neonatal hyperbilirubinemia: A Randomized Controlled Trial - nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/04/065593
Enrollment
150
Registered
2024-04-12
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P599- Neonatal jaundice, unspecified

Interventions

Intervention1: Probiotics ( Darolac sachet) + Phototherapy: Darolac sachet which contains 1.25 billion cells ( lactobacillus acidophilus, lactobacillus rhamnosus, Bifidobacterium longum & saccharomyce

Sponsors

Government Medical College Rajindra Hospital Patiala
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Preterm and term neonates with hyperbilirubinemia (35-40 weeks) 2. Patients with jaundice due to maternal blood type ABO compatibility 3. G6PD deficiency 4. Hypothyroidism 5. Sepsis

Exclusion criteria

Exclusion criteria: 1. Patients with gestational age less than 35 weeks. 2. Patients with severe cardiopulmonary illness. 3. Patients with birth weight less than 2,000 grams. 4. Patients having signs of perinatal asphyxia. 5. Patients with congenital anomalies. 6. Patients whose parents refuse to give written informed consent

Design outcomes

Primary

MeasureTime frame
serum bilirubin level lowering efficacy of probiotics along with phototherapy vs phototheray alone in patients of neonatal hyperbilirubinemiaTimepoint: Day-1, 24 hours, 48 hours and 72 hours

Secondary

MeasureTime frame
change in duration of phototherapy in probiotics along with phototherapy and phototherapy alone treatment groupTimepoint: Day-1, 24 hours, 48 hours and 72 hours

Countries

India

Contacts

Public ContactDr Amanpreet Kaur

Government Medical College & Rajindra Hospital Patiala

jsjasbir9@gmail.com9417212020

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026