Study to compare two different types of block for post surgery pain relief after cesarean section

Comparison of postoperative analgesia for patients undergoing cesarean section with ultrasound-guided quadratus lumborum block-2 vs quadratus lumborum block-3 - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/065566

Enrollment

Registered

2024-04-12

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Quadratus lumborum block Type 2: Quadratus lumborum block Type 2 will be given at the end of cesarean section with 0.3 ml/kg of 0.25 % bupivacaine bilaterally in Group 1 patients and ob

Eligibility

Inclusion criteria

Inclusion criteria: Age 18 to 45 years, ASA II and III patients, pregnancy beyond 34 weeks, weight < 100 kg

Exclusion criteria

Exclusion criteria: Allergy to local anesthetic drugs,obstetric complications (premature rupture of amniotic membranes, premature labor, eclampsia, antepartum hemorrhage, chorioamnionitis, HELLP syndrome), severe systemic diseases, coagulation abnormalities, patients with history of immunosuppression, Patients having intraoperative adverse events like hemorrhage, thromboembolism, bradycardia, allergic reaction etc., weight > 100 kg

Design outcomes

Primary

Measure	Time frame
Time to first bolus of rescue analgesia postoperatively in both approaches of quadratus lumborum blockTimepoint: Patient assessed at 2, 4, 6, 12, 24 hours post block for pain score and rescue analgesia consumption	—

Secondary

Measure	Time frame
Apgar scoreTimepoint: Apgar scores at 1 minute and 5 minutes will be noted;Assess the static and dynamic pain scores post-operativelyTimepoint: Static and dynamic pain scores will be assessed post-operatively for 24 hours at regular time intervals by asking the patient to flex their legs and by turning to one side;No of PCA doses deliveredTimepoint: Actual doses of PCA are delivered within 24 hours of the operation;Time of completion of both types of QLBTimepoint: Total time of completion of QLB 2 and QLB 3;Total amount of rescue analgesia consumedTimepoint: Inj Diclofenac 75 mg iv will be used as rescue analgesia and total number of doses will be noted.;Total number of PCA demandsTimepoint: All the patients will receive PCA infusion maintained with boluses of fentanyl with 10 micrograms per ml. The patients will be provided with a remote controlled hand-held button and there will be a provision of patient controlled boluses of 1ml of 10 micrograms per ml of fentanyl, with a lockout interval of 10 min when needed. Total number of PCA demands will be noted	—

Measure

Time frame

Apgar scoreTimepoint: Apgar scores at 1 minute and 5 minutes will be noted;Assess the static and dynamic pain scores post-operativelyTimepoint: Static and dynamic pain scores will be assessed post-operatively for 24 hours at regular time intervals by asking the patient to flex their legs and by turning to one side;No of PCA doses deliveredTimepoint: Actual doses of PCA are delivered within 24 hours of the operation;Time of completion of both types of QLBTimepoint: Total time of completion of QLB 2 and QLB 3;Total amount of rescue analgesia consumedTimepoint: Inj Diclofenac 75 mg iv will be used as rescue analgesia and total number of doses will be noted.;Total number of PCA demandsTimepoint: All the patients will receive PCA infusion maintained with boluses of fentanyl with 10 micrograms per ml. The patients will be provided with a remote controlled hand-held button and there will be a provision of patient controlled boluses of 1ml of 10 micrograms per ml of fentanyl, with a lockout interval of 10 min when needed. Total number of PCA demands will be noted

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Countries

India

Contacts

Public ContactDr Sukanya Mitra

Government medical college and hospital Chandigarh

drsmitra12@yahoo.com9646121521

Outcome results