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The power of the drug to produce a desired result of cuff around plastic tube inserted into the patients airway with drug after completion of procedure to prevent complication of sore throat

Efficacy of intracuff Dexamethasone on post-operative sore throat : A prospective randomized controlled study - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/04/065557
Enrollment
108
Registered
2024-04-12
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexamethasone: Endotracheal tube cuff to be inflated with Dexamethasone (0.1 mg/kg) and add normal saline till the cuff leak disappears. Control Intervention1: Air: Endotracheal tube cu

Sponsors

Government medical college, Baroda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)ASA I, II, III scheduled for elective surgery 2]Age group between 18 to 60 years 3]Duration of surgery 2 to 3 hours.

Exclusion criteria

Exclusion criteria: 1]Patient Refusal. 2]Patients with history of Smoking, Asthma, recent upper/lower respiratory tract infection, Gastroesophageal reflux disease 3]Patients with laryngeal diseases/surgery 4]Patients with history of tracheostomy 5] difficult intubation 6]Increased risk of aspiration, intraoperatively placement of nasogastric tube 7]Pregnancy 8]Oral Packing 9]Prone Position 10] more than 2 attempts of extubation

Design outcomes

Primary

MeasureTime frame
post-operative laryngotracheal morbidities in terms of sore throat, Coughing, Hoarseness of voice, DysphagiaTimepoint: At end of procedure

Secondary

MeasureTime frame
1]Number of attempts of intubation 2]Volume of air or Dexamethasone used for inflating the ETT cuff at the time of intubation. 3]Cuff pressure when filled with Dexamethasone or air at the time of intubation. 4]Hemodynamic parameter.Timepoint: From baseline till end of procedure

Countries

India

Contacts

Public ContactDr Jalpa Balat

Government medical college, Baroda

jalpadamor53203@gmail.com9909967624

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026