Comparing the pain on injection and pain during root canal treatment on giving normal and cold injection

Effect of topical cooling of the injection site and cold anesthetic administration on onset, anesthetic efficacy and injection pain during infiltration anesthesia of maxillary premolars with symptomatic irreversible pulpitis: A randomized controlled trial. - NIL

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/065545

Enrollment

Registered

2024-04-10

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: cold 2% lignocaine HCl with 1:80,000 epinephrine: One time intervention by applying ice stick over injection site and administration of cold 2% lignocaine HCl with 1:80,000 epinephrine

Eligibility

Inclusion criteria

Inclusion criteria: .Patients with good health in the age group of 20-40 years. 2.Patients with symptomatic irreversible pulpitis of maxillary premolars. 3.Patients with preoperative pain score greater than 54mm as measured on HP-VAS scale.

Exclusion criteria

Exclusion criteria: Individuals with systemic and mental illness. Individuals with known allergy or contraindication to lignocaine. Pregnant and lactating mothers. Individuals who have taken analgesics 12hrs before endodontic procedure. Individuals under barbiturates and benzodiazepine medication. Presence of chronic endodontic lesions in relation to the tooth.

Design outcomes

Primary

Measure	Time frame
Evaluate the onset, anesthetic efficacy and injection pain during administration of cold local anesthesia.Timepoint: Evaluate the onset, anesthetic efficacy and injection pain during administration of cold local anesthesia at the baseline.	—

Secondary

Measure	Time frame
Intergroup comparison of the effects of the anesthesia.Timepoint: Compare the effect of anesthesia in males & females at the baseline.	—

Countries

India

Contacts

Public ContactANJITHA T

Coorg institute of dental sciences

drponnappa@gmail.com9449764068

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026