study which compares two doses of dexmeditomedine drug in combination with fixed dose of ketamine drug delivered as intranasal spray in children for evaluating parental seperation without cry and ease of intravenous cannulation

Prospective randomized atudy to compare two does of dexmedetomidine in combination with standard dose ketamine delivered as atomised intranasal spray in paediatric population for evaluating parental separation without cryand ease of intravenous cannulation. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/065505

Enrollment

Registered

2024-04-10

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Mucosal atomiser spray: Dexmedetomidine and ketamine combination is administered intranasally 45 minutes before procedure. 0.5ml is administered in each nostril Control Intervention1:

Eligibility

Inclusion criteria

Inclusion criteria: ASA status 1and 2

Exclusion criteria

Exclusion criteria: Children less than 1 year and more than 10years Organ dysfunction Congenital heart disease Cardiac arrhythmia Mental retardation

Design outcomes

Primary

Measure	Time frame
Time of successful separation from mother using sedation score at 5minutes interval after premedication, Ease of intravenous cannulation using FLACC scale Timepoint: 0 minutes , 5 minutes , 10 minutes, 15 minutes ,20 minutes and 30 minutes	—

Secondary

Measure	Time frame
Adverse effects, Wakeup behaviourTimepoint: After extubation	—

Countries

India

Contacts

Public ContactMahalakshmi R

Saveetha medical college and hospital

dr_yach@yahoo.co.in9790963362

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026