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A study to compare the efficacy of nanobiofusion gel in the treatment of chronic periodontitis in smokers and non-smokers: A randomized controlled trial

A comparative study to assess the efficacy of nanobiofusion gel in the treatment of chronic periodontitis in smokers and non-smokers: A clinico-microbiological randomized controlled trial - NILL

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/04/065484
Enrollment
30
Registered
2024-04-09
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Test Group (Smokers): Scaling and root planing (SRP) in combination with Nano-Bio Fusion Gingival Gel: A single application of Nanobiofusion gel will be introduced subgingivally within

Sponsors

Dr Leanne Braganca
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1-Systemically healthy participants. 2-Age group: 20–65 years. 3-A minimum of twenty teeth present. 4-Probing pocket depth (PPD) of 5-6mm in two contralateral quadrants. 5-Smoker’s Group: Moderate smokers- 6-10 cigarettes/day & Heavy smokers (More than 11 cigarettes per day) (Jones et al, 2011)

Exclusion criteria

Exclusion criteria: 1-Systemically compromised patients. 2-Patients taking any other medications. 3-Patients with known allergies or hypersensitivity reactions. 4-Pregnant and lactating women. 5-Subjects who underwent periodontal treatment within a period of 6 months. 6-History of antibiotic intake at least 3 months prior. 7-History of use of mouthwashes within 4 weeks before the start of the study.

Design outcomes

Primary

MeasureTime frame
Reduction in probing depthTimepoint: baseline and 3 months

Secondary

MeasureTime frame
Reduction in microbial load of P gingivalis based on number of colony forming unitsTimepoint: baseline and 6 weeks

Countries

India

Contacts

Public ContactDr Leanne Braganca

Goa Dental College and Hospital

jamessamueldental@gmail.com8806595894

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026