Efficacy of rose Bengal dye in addition with mechanical cleaning using laser assisted therapy in implant defects.

Rosebengal Assisted Antimicrobial Photodynamic Therapy as an Adjunct To Mechanical Debridement In Non Surgical Management Of Periimplantitis- A Randomised Control Trial. - Nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/065478

Enrollment

Registered

2024-04-09

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K055- Other periodontal diseases

Interventions

Intervention1: mechanical debridement + Rose Bengal mediated aPDT: Use of Rose Bengal mediated antimicrobial photodynamic therapy post non surgical therapy after baseline evaluation. Total duration

Eligibility

Inclusion criteria

Inclusion criteria: 1 patients above or equal to 20years of age. 2 Absence of relevant medical conditions. 3 Initial peri-implantitis a pocket probing depth (PPD) of 4–6 mm with concomitant bleeding on probing (BoP) at 1 peri-implant site and radiographic marginal bone loss ranging from 0.5 to 2 mm between delivery of the suprastructure and pre-screening appointment. 4 Implant in function for at least 1 year. 5 Solid screw bone level titanium implants with sandblasted and acid etched surface (Straumann dental implant system)

Exclusion criteria

Exclusion criteria: (1) Uncontrolled medical conditions. (2) Pregnant or lactating females. (3) Tobacco smoking. (4) Untreated periodontal conditions. (5) Use of antibiotics in the past 3 months. (6) Subjects treated for more than 2 weeks with any medication known to affect soft tissue conditions (e.g. phenytoin, calcium antag- onists, cyclosporin, coumadin and non- steroidal anti-inflammatory drugs) within 1 month of the baseline examination. (7) Peri-implant mucositis defined as the absence of radiographic marginal bone loss between delivery of the suprastructure and pre-screening appointment. (8) Failure to sign written informed consent.

Design outcomes

Primary

Measure	Time frame
1) Pocket Probing Depth (PPD). (2) Clinical Attachment Level (CAL). (3) Mucosal recession (REC). (4) Bleeding on Probing (BoP) (5) Modified Plaque Index (mPlI)Timepoint: Baseline 3 months 6 months	—

Secondary

Measure	Time frame
Microbial colony count Inflammatory bio marker levelsTimepoint: Baseline 3 months 6 months	—

Countries

India

Contacts

Public ContactDr Arvina Rajasekar

Saveetha Dental College and Hopsital, SIMATS University

arvinar.sdc@saveetha.com9486442309

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026