Health Condition 1: J980- Diseases of bronchus, not elsewhere classified
Conditions
Interventions
Intervention1: Cryoprobe application prior to biopsy of target lesion: One-time
Control Intervention1: Conventional forceps biopsy of target lesion (without prior cryoprobe application): One-time
Sponsors
Mayank Mishra
Girish Sindhwani
Nilotpal Chowdhury
Eligibility
Inclusion criteria
Inclusion criteria: Adults more than or equal to 18 years of age undergoing flexible bronchoscopic forceps biopsy of a definite exophytic / definite infiltrative endobronchial lesion under local or general anesthesia.
Exclusion criteria
Exclusion criteria: Mucosal irregularities, hypervascular lesions like carcinoid. No endobronchial lesion found on flexible bronchoscopy or lesion deemed unamenable to biopsy by the operator. Not giving informed consent for the procedure. Uncooperative patient. Pre-procedural hypoxemia. Uncontrolled baseline hypertension. Symptomatic coronary artery disease or high cardiac risk for procedure. On anticoagulants. Uncorrectable coagulopathy. Pacemaker or implantable cardioverter defibrillator in situ.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of bleeding after flexible bronchoscopic forceps biopsy of endobronchial lesion with or without prior application of cryoprobe to the lesionTimepoint: 0 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Presence of artefacts/tissue damage in the biopsy specimenTimepoint: 0 days;Interpretability of biopsy specimenTimepoint: 0 days;Diagnostic yield on histopathological examinationTimepoint: 0 days | — |
Countries
India
Contacts
Public ContactMayank Mishra
All India Institute of Medical Sciences, Rishikesh
Outcome results
None listed