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Role of topical nitroglycerin ointments to prevent flap necrosis after mastectomy surgery

Role of topical nitroglycerin in the prevention and treatment of post mastectomy skin flap necrosis- a prospective comparative study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/04/065465
Enrollment
90
Registered
2024-04-09
Start date
Unknown
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C50- Malignant neoplasm of breast

Interventions

Intervention1: Topical nitroglycerin: 2% formulation of topical nitroglycerin to be applied topically three times a day for 5 days from 2nd post operative day Control Intervention1: Povidone iodine: T

Sponsors

Govt Stanley medical college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing mastectomy

Exclusion criteria

Exclusion criteria: History of thromboembolic events Coronary artery disease patients Uncontrolled comorbidities History of hypersensitivity reactions

Design outcomes

Primary

MeasureTime frame
1. Incidence of post mastectomy skin flap necrosis in patients using topical nitroglycerinTimepoint: 4 weeks—

Secondary

MeasureTime frame
Role of topical nitroglycerin in treating post mastectomy skin flap necrosis by preventing the progression of necrosis & reducing the need for wound debridement whe compared to povidone iodineTimepoint: 4 weeks—

Countries

India

Contacts

Public ContactDr Sumaiya Fathima

Govt Stanley Medical College

drbspriya@yahoo.co.in94444086644

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Sep 19, 2026