Health Condition 1: C67- Malignant neoplasm of bladder
Conditions
Interventions
Intervention1: Holmium Laser En Bloc resection of bladder tumor (HoLERBT): Procedure Overview:
Preoperative Assessment: Patients meeting inclusion criteria are evaluated for fitness for anesthesia, i
Sponsors
Post Graduate Institute of Medical Education & Research, Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: Patients with Urinary Bladder mass presenting for the first time with single tumor on imaging and the tumor size less than 4 cm.
Exclusion criteria
Exclusion criteria: 1) Patients who have received any form of intravesical/systemic chemotherapy elsewhere. 2) Patients with obvious extravesical disease on CECT (radiologically more than or equal to T3) 3) Tumor size more than 4 cm.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy of ThuLERBT in comparison with HoLERBT in tumor histopathological staging and detrusor muscle sampling for biopsy.Timepoint: operation time ,Number of growths,Morphology, Mean diameter of tumor (cm), Tumor location, Completion of resection Obturator jerk Bladder perforation (if any) | — |
Secondary
| Measure | Time frame |
|---|---|
| Periprocedural complications between ThuLERBT and HoLERBT in terms of bleeding and obturator nerve jerk.Timepoint: real-time as the interventions are being carried out;Incidence of residual tumour and tumour upstaging in restage HoLERBT / ThuLERBTTimepoint: During the postoperative period, specifically when the restaging procedures are performed | — |
Countries
India
Contacts
Public ContactProf Dr Uttam K Mete
Postgraduate Institute of Medical Education and Research, Chandigarh, India
Outcome results
None listed