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A study to find out the relation between the inflammatory markers and severity of meconium aspiration disease in newborns and its outcome.

A prospective single centre study of correlation between inflammatory markers and various severity grades of meconium aspiration syndrome (mas) & their outcome - NIL

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/04/065447
Enrollment
69
Registered
2024-04-09
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P240- Meconium aspiration

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

Bhaktivedanta Hospital and Research Institute
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Term and post term neonates with meconium stained amniotic fluid &/or MAS will be included.

Exclusion criteria

Exclusion criteria: 1.Preterms 2.Term neonates with:Transient tachypnoea of new-born, Hypoxic ischemic encephalopathy, congenital heart disease, congenital defects of any other organ, Inborn Error of metabolism surgical Pathology, New-born with hyaline membrane disease Infant of diabetic mother, Polycythaemia New born with respiratory distress with any other etiology or confounding factors other than MAS

Design outcomes

Primary

MeasureTime frame
Changes in the inflammatory markers with severity grades of MAS. Value of inflammatory markers in respect to outcome parameters- nicu stay of child, associated complications-PPHN, pnemothorax, O2days,Ventilator days, cpap days,inotropes days, need of surfactant, need of HFO, ECMO, history of fetal distress, APGAR score at 1min and 5 mins.Timepoint: 24hrs, 48hrs, 5th day of birth

Secondary

MeasureTime frame
1.coincidence of sepsis with MAS with their respective inflammatory markers 2.value of inflammatory markers in MSAFTimepoint: 48hrs of birth

Countries

India

Contacts

Public ContactDr Deepali Shukla

Bhaktivedanta Hospital and Research Institute

samratbvh@rediffmail.com9321701322

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026