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Assessment of Heart function and volume during Heart surgery using echocardiographic contrast agent.

Contrast enhancement for intraoperative quantitative assessment of left ventricular volumes using transesophageal echocardiography. - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/04/065434
Enrollment
52
Registered
2024-04-09
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I25- Chronic ischemic heart disease

Interventions

Control Intervention1: Contrast enhanced 2D transesophageal echocardiography: Transesophageal echocardiography Control Intervention2: Conventional 2D Transesophageal echocardiography: Transesophageal

Sponsors

Sree Chitra Tirunal Institute for Medical Sciences and Technology,Trivandrum
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All Adult patients scheduled for elective coronary artery bypass grafting Normal sinus rhythm.

Exclusion criteria

Exclusion criteria: Emergency surgeries Redo surgeries Patients not willing to participate in study More than mild AR, MR or TR Any allergies to the contrast agents Contraindications for SonoVue administration (as recommended by the manufacturers)-Unstable coronary artery disease, acute Cardiac failure, right to Left shunts, severe pulmonary arterial htn (RVSP > 55mmHg on TTE). Patient with arrhythmias. Contraindication to TEE probe placement like esophageal strictures, esophageal varices, esophageal tumors, gastric ulcer, previous esophagectomy, esophageal diverticulum, tracheoesophageal fistula, previous bariatric surgery, hiatus hernia, large descending thoracic aortic aneurysm, unilateral vocal cord paralysis, esophageal varices, post-radiation therapy.

Design outcomes

Primary

MeasureTime frame
To evaluate whether injection of echo contrast increases the estimated LV volumes on 2D echocardiography compared to those without the use of contrast.Timepoint: after induction of anaesthesia, before going on cardiopulmonary bypass.

Secondary

MeasureTime frame
To compare intra-observer and inter-observer variability in the measurement of LV volumes with and without echo contrast.Timepoint: after induction of anaesthesia, before going on cardiopulmonary bypass.;To compare static cardiac output measured by Modified Simpson’s method with or without echo contrast with LVOT dynamic cardiac output.Timepoint: after induction of anaesthesia, before going on cardiopulmonary bypass.;To evaluate whether the echo contrast increases the 3D echocardiographic estimation of LV volumesTimepoint: after induction of anaesthesia, before going on cardiopulmonary bypass.

Countries

India

Contacts

Public ContactDr Udit Khajuria

Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum

uditkhajuria95@gmail.com9596640802

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026