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Assessing Salivary Maresins and Protectins Response to gum treatment in Participants with gum and alveolar bone disease, with and without Type 2 Diabetes: An Observational Study

Effect of periodontal therapy on the salivary levels of Maresins and Protectins in periodontitis patients with and without type 2 diabetes mellitus: an observational study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/04/065414
Enrollment
42
Registered
2024-04-08
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E116- Type 2 diabetes mellitus with other specified complications

Interventions

Intervention1: Test group: EFFECT OF PERIODONTAL THERAPY ON THE SALIVARY LEVELS OF MARESINS AND PROTECTINS IN PERIODONTITIS PATIENTS WITH TYPE 2 DIABETES MELLITUS Intervention2: NIL: NIL Intervention

Sponsors

Kishore STR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients of both genders and age group 35-65 years. 2.Patients with Stage II and stage III generalised periodontitis with interdental clinical attachment loss = 3mm. 3.Control group (systemically healthy periodontitis patients) 4.Test group ( periodontitis patients with type 2 diabetes mellitus with HbA1c = 6.5%). 5.Patients with more than 20 teeth . 6.Patients who are complying with oral hygiene instructions and periodontal recall. 7.Patients who are willing to participate in the study.

Exclusion criteria

Exclusion criteria: 1.Pregnant and lactating women. 2.Patients using medication affecting the periodontal status. 3.Patients with history of periodontal therapy for the past six months. 4.Patients with immunodeficiency disorders and other inflammatory conditions like inflammatory bowel disorders, inflammatory rheumatoid disorders, cancers, COPD will be excluded from the study. 5.Patient with the habit of smoking and chewing / other oral lesions such as periodontal abscess are not to be included. 6.History of radiation therapy to the head and neck 7.Patients who are not willing to participate in the study.

Design outcomes

Primary

MeasureTime frame
To evaluate the salivary levels of maresins and protectins at baseline and six weeks after Phase 1 periodontal therapy within the controls and the test groups.Timepoint: Baseline and 6 weeks—

Secondary

MeasureTime frame
To compare the salivary levels of maresins and protectins between the control and test groups before and after non surgical periodontal therapyTimepoint: Baseline and 6 weeks—

Countries

India

Contacts

Public ContactS Sangeetha

DEPARTMENT OF PERIODONTOLOGY, SRM DENTAL COLLEGE , RAMAPURAM, CHENNAI, TAMILNADU 600089 India

sangeetha_doc@yahoo.com9884563217

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026