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Efficacy Of Leucocyte Rich – Platelet Rich Plasma on Pressure Ulcers in Trauma ICU Patients.

Efficacy Of Leucocyte Rich – Platelet Rich Plasma on Pressure Ulcers in Trauma ICU Patients - A Prospective Parallel Design Randomized Trail ?.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/04/065401
Enrollment
42
Registered
2024-04-08
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L894- Pressure ulcer of contiguous siteof back, buttock and hip

Interventions

Intervention1: LEUCOCYTE RICH – PLATELET RICH PLASMA (LR-PRP): Leucocyte Rich-Platelet Rich Plasma will be injected into the margin and floor of the pressure ulcers after cleaning, washing and debridi

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) As per study protocol, Patients with Pressure ulcers GRADE more than or equal to 3 were chosen irrespective of the site 2) age more than or equal to 18 years old

Exclusion criteria

Exclusion criteria: 1) Patients with poor compliance; 2) Patients with unstable vital signs 3) Patients combined with severe cardiopulmonary disease; 4) Pregnant and lactating women. 5) Cancer 6) Autoimmune diseases 7) Chemotherapy or radiotherapy (Hormone or immunosuppressant treatment) 8) Treatment with anti-platelet agents, platelet disorders, thrombocytopenia, anti- retro viral drugs, bone marrow aplasia, uncontrolled diabetes 9) Had existing Hemorrhagic diseases 10) Sepsis. 11) Other local criteria included osteomyelitis

Design outcomes

Primary

MeasureTime frame
Efficacy of Buffy – coat (Leucocyte Rich) Platelet Rich Plasma in pressure ulcers.Timepoint: 0day, 7th day, 14th day, 21st day, 28th day

Secondary

MeasureTime frame
1. To compare the healing rate 2. To compare the duration taken for healing 3. To compare the physical outcomesTimepoint: 0day, 7th day, 14th day, 21st day, 28th day

Countries

India

Contacts

Public ContactHema Brahadeeswari G

Institute of Medical Sciences, Banaras Hindu University.

ghanshyamx@rediffmail.com8608617315

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026