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Using Tranexamic Acid with Oxytocin to Prevent Excessive Bleeding After C-Sections

Tranexamic Acid as an add on therapy to Intramuscular Oxytocin in Prevention of Postpartum Hemorrhage in Cesarean Section

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/04/065359
Enrollment
200
Registered
2024-04-08
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O722- Delayed and secondary postpartum hemorrhage

Interventions

Intervention1: Tranexamic acid: Tranexamic acid is an antifibrinolytic agent it works by blocking the breaking down of clots. Injectable tranexamic acid 1 gm intravenous after the delivery of fetus. C

Sponsors

jawaharlal nehru medical college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Scheduled or unscheduled cesarean delivery of all age groups and partiy Singleton or twin gestation

Exclusion criteria

Exclusion criteria: Severe medical and surgical complications History of allergy to tranexamic acid History of thrombi-embolic disorders. Antenatal complications like, abnormal placenta placenta-previa, placenta abruption, adherent placenta, severe preeclampsia, Multiple pregnancies, macrosomia, polyhydramnios, Fibroid uterus or gynecological disorders complicating pregnancy.

Design outcomes

Primary

MeasureTime frame
Difference in blood loss between the two groups In women receiving tranexamic acid In women receiving placebo Post operatively up to 6 hours in the same two groups Side effects related to drug used.. Timepoint: 6 HOURS

Secondary

MeasureTime frame
The difference in following parameters in the two groups Hemoglobin/haematocrit Need for additional uterotonics Need for blood transfusion Timepoint: 6 HOURS

Countries

India

Contacts

Public ContactDr Aditi Singh Thakur

datta meghe institute of higher education and research

surobgy@gmail.com7887519832

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026