Interventional study to assess the reduction in Anaesthesia requirement in participants due to Magnesium.

Effect of MgSO4 in reducing the requirement of Inhalational agent in head and neck cancer surgery with free tissue transfer - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2024/04/065347

Enrollment

102

Registered

2024-04-08

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx Health Condition 2: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx

Interventions

Intervention1: Mgso4: A standard solution with concentration of 100mg/ml will be prepared Inj. MgSO4 (Study drug) bolus will be given 45mg/kg over 10 mins. After this maintenance dose 10mg/kg/hr will

Eligibility

Inclusion criteria

Inclusion criteria: Patient with ASA grade I and II aged between 18 to 60 years of age Undergoing head and neck cancer surgery with free tissue transfer.

Exclusion criteria

Exclusion criteria: Patient refusal patient on beta blocker therapy Patient with coronary Artery disease Patient with CKD Patient with Neuromuscular Disorders Patient with prolonged QTc patient with history of drug abuse Patients with arrhythmias

Design outcomes

Primary

Measure	Time frame
Reduction in requirement of inhalational agent in maintenance of anesthesia in head and neck surgery with free tissue transferTimepoint: Baseline, every hour till the end of surgery	—

Secondary

Measure	Time frame
Hemodynamic stability in study groupTimepoint: 15 minutes	—

Countries

India

Contacts

Public ContactPushplata Gupta

Bhagwan mahaveer cancer hospital and research center

drpushplatagupta4@gmail.com9829098288

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026