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Effect of Transverse Thoracis Muscle Plane Block on requirement of pain medication during and after the surgery

A Randomised controlled study for efficacy of bilateral transverse thoracis muscle plane block on perioperative requirement of fentanyl in patients undergoing cardiac surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/04/065343
Enrollment
60
Registered
2024-04-08
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I00-I99- Diseases of the circulatory system Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Transverse Thoracis Muscle Plane Block (TTMB): Transverse Thoracis Muscle Plane Block will be performed bilaterally under USG guidance with patient in supine position after induction of

Sponsors

Department of Anesthesiology and Critical Care SMS Medical College and Attached Hospitals Jaipur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient undergoing planned cardiac surgery via median sternotomy, patient giving informed consent for study, weight 40 to 75 kg, ASA PS grade 2 or 3

Exclusion criteria

Exclusion criteria: Patient undergoing CABG using Internal Mammary Artery, Non-consenting patient, patient should not be a part of other study, allergic to study drugs, endocrine, metabolic, neurological and psychiatric disorders, patients on anti coagulant drugs or coagulopathy

Design outcomes

Primary

MeasureTime frame
Mean Dose of Fentanyl Intraoperative and postoperative periodTimepoint: At end of surgery, 48 hours postoperative

Secondary

MeasureTime frame
Mean Hemodynamic Variables - mean heart rate, mean systolic, diastolic and mean blood pressuresTimepoint: Pre operative, 2 mins after intubation, 2 mins after TTMB, 15 min, 30 min, every 15 mins till patient goes on Cardiopulmonary bypass, 0 mins after coming off pump, every 15 mins till surgery is complete. Immediate Post operative, 2 hrs, 4 hrs, 8 hrs, 12 hrs, 24 hrs, 36 hrs, 48 hrs;Mean PEFR at time of extubationTimepoint: At time of extubation

Countries

India

Contacts

Public ContactDr Harsh Mittal

SMS Medical College and Attached hospitals

Dranjumsaiyed@gmail.com9214021930

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026