Health Condition 1: M170- Bilateral primary osteoarthritis of knee
Conditions
Interventions
Intervention1: Injection of bone marrow aspirate concentrate: About single dose 4ml each of bone marrow aspirate concentrate will be injected into the intraarticular and subchondral injection region u
Sponsors
Arulkumar Nallakumarasamy
Eligibility
Inclusion criteria
Inclusion criteria: Patients OA knee – Grade II and III. Primary OA knee patients not responding to analgesics Patients who are willing to take part in the study after informed consent
Exclusion criteria
Exclusion criteria: 1) Post-traumatic knee Stiffness 2) History of Infective joint disease 3) Patients with a history of previous surgeries on the knee. 4) Co-morbid / Pathology of ipsilateral Hip/ foot joint pathology • Patients with rheumatoid arthritis, inflammatory arthritis or polyarticular arthritis, and autoimmune diseases 5) Any other defect of the ipsilateral limb like – Shortening etc. 6) Patients with h/o prior corticosteroid injection at a treatment site within 3 months of duration
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess change in patient-reported outcome measures such as VAS, WOMAC, and KOOS, from baseline to different follow-up time pointsTimepoint: At post-procedure, 1 week, 1 months, 3 months, 6 months & 1 year | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the healing of subchondral bone lesions (bone marrow lesions) & the integrity of cartilage during pre and post-procedural follow-up with intraarticular and subchondral BMAC in primary osteoarthritis knees via MOCART at a 1-year time point using MRI. Timepoint: 1 year | — |
Countries
India
Contacts
Public ContactDr V R Ravi
Department of Orthopaedics, Datta Meghe Institute of Medical Sciences
Outcome results
None listed