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Comparison of Clarithromycin Gel and Chlorhexidine Gel after full mouth cleaning in pyorrhea patients.

Comparative evaluation of Clarithromycin Gel and Chlorhexidine Gel as local drug delivery agents as an adjunct to scaling and root planing in the management of patients with chronic periodontitis (stageIII gradeB)-A clinico-microbiological study. - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/04/065282
Enrollment
26
Registered
2024-04-05
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K05- Gingivitis and periodontal diseases Health Condition 2: Z77-Z99- Persons with potential health hazards related to family and personal history and certain conditions influencing health status

Interventions

Intervention1: Chlorhexidine gel: Chlorhexidine Gel as local drug delivery agents as an adjunct to scaling and root planing in the management of patients with chronic periodontitis stageIII gradeB at

Sponsors

Dr Aishwarya Sawai
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: A minimum of 20 teeth should be presented in the mouth of the patients Generalized Chronic Periodontitis StageIII GradeB patient with at least 2 non-adjacent teeth in 2 contralateral quadrants with a Clinical attachment level of more than 3mm and Probing pocket depth of 4-6mm Patients with no history of allergies

Exclusion criteria

Exclusion criteria: Patients suffering from any known systemic diseases Smokers and alcoholic patients Medication taken by the patient that would induce gingival enlargement Pregnancy or lactating female patients Patients who have received surgical or nonsurgical periodontal therapy in the last 3 months before the baseline visit Patients who received systemic antimicrobial therapy in the last 2 months before entry Patients who have received clarithromycin and chlorhexidine gel in the past Patients who have received any antibiotics chemotherapeutic mouth rinse or oral irrigation during the past 3 months Patients allergic to any medication

Design outcomes

Primary

MeasureTime frame
Change in microbial parameters using conventional PCR techniqueTimepoint: At baseline and 6 weeks

Secondary

MeasureTime frame
Change in clinical parameters Plaque index (PI) Gingival index (GI) Modified sulcular bleeding index (mSBI) Probing pocket depth (PPD) Clinical attachment levels(CAL)Timepoint: At baseline 6 weeks and 3 months

Countries

India

Contacts

Public ContactDr Aishwarya Sawai

Dr HSRSM Dental College And Hospital

mahajanimonica@gmail.com9322855839

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026