Health Condition 1: C15-C26- Malignant neoplasms of digestive organs
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients aged = 18 to 75 years, 2. Patients of either gender, 3. Patients with metastatic colon cancer confirmed on histology with a colon biopsy at time of colonoscopy 4. Patients planned for upfront systemic therapy. 5. Patients with Karnofsky performance status 70% or higher and adequate hematological and end-organ function 6. Availability of sufficient tumor tissue to carry out mutational profiling. 7. Patients willing to participate in the study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with recurrent colon cancer 2. Patients with previously treated other malignancies or who have received previous systemic treatment 3. Patients with any underlying hereditary syndromes 4. Pregnant women; 5. Patients who refuse to give consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The differences in incidence of mutation in left versus right sided colon cancer would reflect different biological characteristics of proximal and distal colon cells which in turn determine different responses to treatmentTimepoint: 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| NILTimepoint: NIL | — |
Countries
India
Contacts
Public ContactDr Shina Goyal
Medanta The Medicity
Outcome results
None listed