Health Condition 1: K929- Disease of digestive system, unspecified Health Condition 2: N289- Disorder of kidney and ureter, unspecified Health Condition 3: R99- Ill-defined and unknown cause of mortality Health Condition 4: A498- Other bacterial infections of unspecified site Health Condition 5: G988- Other disorders of nervous system Health Condition 6: J22- Unspecified acute lower respiratory infection Health Condition 7: I999- Unspecified disorder of circulatory system
Conditions
Interventions
Intervention1: Collection of blood sample for estimation of drug levels of vancomycin: Collection of blood sample for estimation of drug levels of vancomycin in 12 patients. Details given in next sect
Sponsors
NIL
Eligibility
Inclusion criteria
Inclusion criteria: 1. All consecutive patients in the age group of more than 1 month to 12 years who are newly admitted to the PICU and are started on antibacterial agents. 2. For estimation of vancomycin levels, 12 patients on vancomycin will be enrolled from amongst the above study participants.
Exclusion criteria
Exclusion criteria: Patients for whom the parents / guardians are not willing to give informed consent for participation will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Utilization of antibacterial agents as per the World Health Organization (WHO) drug use indicators. 2. Indications of using antibacterial agents (empirical OR definitive OR prophylactic). 3. Indications for change of antibacterial agents and escalation OR de-escalation of antibacterial agents. Timepoint: Duration of the PICU stay till discharge or death | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Estimate the drug levels of vancomycin. 2. Off-label use of antibacterial agents Timepoint: Duration of the PICU stay till discharge or death | — |
Countries
India
Contacts
Public ContactSubashree S
Seth G.S. Medical College and KEM Hospital
Outcome results
None listed